Consumer health information is a critical tool for ensuring a high level of public education regarding disease spread and effects. However, not all sources sufficiently use evidence and recommendations and outline the impact of a particular disease on a population. By comparing two different sources from related websites, it is possible to establish which one uses a more suitable approach to explaining an illness. This essay will provide DISCERN and readability analysis of human immunodeficiency virus (HIV) consumer guidelines by Mayo Clinic and UpToDate websites.